Carbapenem Resistance inKlebsiella pneumoniaeNot Detected by Automated Susceptibility Testing
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منابع مشابه
Carbapenem Resistance in Klebsiella pneumoniae Not Detected by Automated Susceptibility Testing
Detecting beta-lactamase-mediated carbapenem resistance among Klebsiella pneumoniae isolates and other Enterobacteriaceae is an emerging problem. In this study, 15 blaKPC-positive Klebsiella pneumoniae that showed discrepant results for imipenem and meropenem from 4 New York City hospitals were characterized by isoelectric focusing; broth microdilution (BMD); disk diffusion (DD); and MicroScan,...
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The Acinetobacter baumannii-calcoaceticus complex (ABC) is associated with increasing carbapenem resistance, necessitating accurate resistance testing to maximize therapeutic options. We determined the accuracy of carbapenem antimicrobial susceptibility tests for ABC isolates and surveyed them for genetic determinants of carbapenem resistance. A total of 107 single-patient ABC isolates from blo...
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Klebsiella pneumoniae showing high resistance to all β-lactams except imipenem, designated as ISMRK (imipenem-susceptible meropenem-resistant Klebsiella) is emerging in Japan. The carbapenem resistance of ISMRK cannot be screened by the Vitek and the RAISUS rapid automated susceptibility test systems, which may lead to inappropriate antimicrobial therapy, resulting in compromised patient outcomes.
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Background: Once identified as Staphylococcus aureus, it is imperative to understand their methicillin resistance status for institution of appropriate therapy. Conventional disc diffusion tests may not accurately identify MRSA strains and may not be in concordance with PCR results. Objectives: Relative abilities of phenotypic and molecular methods to detect MRSA strains was evaluated to unders...
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Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, As...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2006
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1208.060291